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dc.date.accessioned 2022-02-17T17:56:10Z
dc.date.available 2022-02-17T17:56:10Z
dc.date.issued 2013
dc.identifier.uri http://sedici.unlp.edu.ar/handle/10915/131291
dc.description.abstract Autophagy plays an important role in human pathologies, such as miopathies and neurodegenerative diseases. Moreover, metabolic disease processes such as diabetes and pancreatitis, as well as tumor cells and cancer chemotherapy, activate autophagy. Furthermore, a selective type of autophagy of pancreatic zymogen granules has been discovered and characterized as a protective cellular process triggered by acute pancreatitis. In this review we describe the physiological bases and molecular mechanisms in the autophagic process and the possible role of autophagy in human disease. Understanding the events and molecular mechanisms of this complex cellular process will help in the design of new strategies for more effective diagnosis and treatment. en
dc.format.extent 59-71 es
dc.language en es
dc.subject Autophagy es
dc.subject VMP1 es
dc.subject Zymophagy es
dc.subject mTOR es
dc.title Autophagy, physiology and cell pathology en
dc.type Articulo es
sedici.identifier.issn 1669-5410 es
sedici.creator.person Vaccaro, María Inés es
sedici.subject.materias Ciencias Médicas es
sedici.description.fulltext true es
mods.originInfo.place Sociedad Argentina de Fisiología es
sedici.subtype Articulo es
sedici.rights.license Creative Commons Attribution 4.0 International (CC BY 4.0)
sedici.rights.uri http://creativecommons.org/licenses/by/4.0/
sedici.description.peerReview peer-review es
sedici.relation.journalTitle Physiological Mini Reviews (PMR) es
sedici.relation.journalVolumeAndIssue vol. 6, no. 7 es


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Creative Commons Attribution 4.0 International (CC BY 4.0) Excepto donde se diga explícitamente, este item se publica bajo la siguiente licencia Creative Commons Attribution 4.0 International (CC BY 4.0)